Total 4 theses and 72 articles.

Theses

Brück A. Cognitive impairment in early Parkinson's disease. A positron emission tomography and magnetic resonance imaging study. Doctoral dissertation. Turku: Turun yliopisto, 2005. Annales Universitatis Turkuensis D. Vol. 659. 70 p

Hirvonen J. Brain dopamine receptors and genetic risk for schizophrenia. Doctoral dissertation. Turku: Turun yliopisto, 2005. Annales Universitatis Turkuensis D. Vol. 687. 79 p.

Laaksonen M. The acute effects of exercise on skeletal muscle blood flow. Positron emission tomography studies in healthy subjects. Doctoral dissertation. Turku: Turun yliopisto, 2005. Annales Universitatis Turkuensis D. Vol. 653. 68 p.

Långsjö J. The effects of ketamine on cereberal blood flow and metabolism. Doctoral dissertation. 2005. Annales Universitatis Turkuensis. Series D. Vol. 661. 93 p.

Articles

Aalto, S., Brück, A., Laine, M., Någren, K., & Rinne, J. 2005: Frontal and temporal dopamine release during working memory and attention tasks in healthy umans: a positron emission tomography study using the high-affinity dopamine D2 receptor ligand 11C)FLB 457. J Neurosci 25: 2471-2477. [C]

Aalto, S., *Ihalainen, J., Hirvonen, J., Kajander, J., Scheinin, H., *Tanila, H., Någren, K., Vilkman, H., *Gustafsson, LL., Syvälahti, E., & Hietala, J. 2005: Cortical glutamate-dopamine interaction and ketamine-induced psychotic symptoms in man. Psychopharmacology 182: 375-383. [C]

Aalto, S., *Wallius, E., *Näätänen, P., *Hiltunen, J., Metsähonkala, L., *Sipilä, H., & Karlsson, H. 2005: Regression analysis utilizing subjective evaluation of emotional experience in PET studies on emotion. Brain Res Brain Res Protoc 15: 142-154. [C]

*Bax, JJ., *Abraham, T., *Barold, S., *Breithardt, OA., *Fung, JWH., *Garrigue, S., *Gorcsan, J., *Hayes, D., *Kass, DA., Knuuti, J., *Leclercq, C., *Linde, C., *Mark, D., *Monaghan, M., *Nihoyannopoulos, P, *Schalij, MJ., *Stellbrink, C., *Yu, CM. 2005: Cardiac Resynchronization Therapy, PART 1- Issues before device implantation. J Am Coll Cardiol 46(12): 2153-67 [C]

*Bax, JJ., *Abraham, T., *Barold, S., *Breithardt, OA., *Fung, JWH., *Garrigue, S., *Gorcsan, J., *Hayes, D., *Kass, DA., Knuuti, J., *Leclercq, C., *Linde, C., *Mark, D., *Monaghan, M., *Nihoyannopoulos, P., *Schalij, MJ., *Stellbrink, C., *Yu, CM. 2005: Cardiac Resynchronization Therapy, PART 2 - Issues during and after device implantation and unresolved questions. J Am Coll Cardiol 46(12): 2168-82 [C]

Brück, A., Aalto, S., *Nurmi, E., Bergman, J., & Rinne, J. 2005: Cortical 6-((18)F)fluoro-l-dopa uptake and frontal cognitive functions in early Parkinson's disease. Neurobiol Aging 26: 891-898. [C]

*Grönholm, P., Rinne, JO., Vorobyev, V., & Laine, M. 2005: Naming of newly learned objects: A PET activation study. Cognitive Brain Res 25: 359-371. [C]

Hannukainen, J., Kalliokoski, K., Nuutila, P., *Fujimoto, T., *Kemppainen, J., Viljanen, T., Laaksonen, M., Parkkola, R., Knuuti, J., & Kjaer, M. 2005: In vivo measurements of glucose uptake in human Achilles tendon during differents exercise intensities. Int J Sports Med 26: 727-731. [C]

Hannukainen, J., *Kujala, U., *Toikka, J., Heinonen, O., *Kapanen, J., Vahlberg, T., Kaprio, J., & Kalliokoski, KK. 2005: Cardiac structure and function in monozygotic twin pairs discordant for physical fitness. J Appl Physiol 99:535-541. [C]

*Hesse, B., *Tagil, K,, *Cuocolo, A., *Anagnostopoulos, C., *Bardies, M., *Bax, J., *Bengel, F., *Busemann Sokole, E., *Davies, G., *Dondi, M., *Edenbrandt, L., *Franken, P., *Kjaer, A., Knuuti, J., *Lassmann, M., *Ljungberg, M., *Marcassa C, *Marie PY., *McKiddle, F., *O'Connor, M., *Prvulovich, E., *Underwood, R., & *van Eck-Smit, B. 2005: EANM/ESC procedural guidelines for myocardial perfusion imaging in nuclear cardiology. Eur J Nucl Med Mol Imaging 32(7):855-897. [C]

Hietala, J. 2005: Vakavat mielenterveyden häiriöt tutkimuksellisena ja hoidollisena haasteena. Erikoislääkäri 15(5): 207-208. [c]

Hietala, J., Nyman, MJ., Eskola, O., Laakso, A., Grönroos, T., Oikonen, V., Bergman, J, Haaparanta, M., Forsback, S., Marjamäki, P., Lehikoinen, P., *Goldberg, M., *Burns, D., *Hamill, T., *Eng, WS., *Coimbra, A., *Hargreaves, R., & Solin, O. 2005: Visualization and quantification of NK1-receptors in the human brain. Mol Imag Biol 31 :1-11. [C]

Hirvonen, J. *van Erp, TMG., Huttunen, J., Aalto, S., Någren, K., *Huttunen, M., *Lönnqvist, J., Kaprio, J., Hietala, J., & Cannon, TD. 2005: Increased caudate dopamine D2 receptor availability as a genetic marker for schizophrenia. Arch Gen Psychiatry 62: 371-378. [C]

Ingman, K., Hagelberg, N., Aalto, S., Någren, K., *Juhakoski, A., *Karhuvaara, S., Kallio, A., Oikonen, V., Hietala, J., & Scheinin, H. 2005: Prolonged central mu-opioid receptor occupancy after single and repeated nalmefene dosing. Neuropsychopharmacology 30: 2245-2253. [C]

*Islam, Md.S., Raitakari, OT., Juonala, M., Kähönen, M., Hutri-Kähönen, N., *Collings, A., Aalto-Setälä, K., Kontula, K., Marniemi, J., Viikari, JSA., & Lehtimäki T. 2005: Apolipoprotein A-I/C-III/A-IV SstI and apolipoprotein B XbaI polymorphisms and their association with carotid artery intima-media thickness in the Finnish population. The Cardiovascular Risk in Young Finns Study. Atherosclerosis: 180:79-86. [C]

Järvenpää, T., Rinne, JO., Koskenvuo, M., Räihä, I., & Kaprio, J. 2005: Binge drinking in midlife and dementia risk. Epidemiology 16(6): 766-771. [C]

Kaasinen, V., *Maguire, RP., Kurki, T., Brück, A., & Rinne, JO. 2005: Mapping brain structure and personality in late adulthood. Neuroimage 24: 315-322. [C]

Kalliokoski, K., Knuuti, J., & Nuutila, P. 2005: Relationship between muscle blood flow and oxygen uptake during exercise in endurance-trained and untrained men. J Appl Physiol: 98:380-383. [C]

Kalliokoski, KK., *Langberg, H., *Ryberg, AK., *Scheede-Bergdahl, C., *Doessing, S., *Kjaer, A., *Boushel, R., & *Kjaer, M. 2005: The effect of dynamic knee-extension exercise on patellar tendon and quadriceps femoris muscle glucose uptake in humans studied by positron emission tomography. J Appl Physiol 99: 1189-1192. [C]

Kalliokoski, RJ., Kalliokoski, KK., Sundell, J., Engblom, E., Penttinen, M., Kantola, I., Raitakari, OT., Knuuti, J., & Nuutila, P. 2005: Impaired myocardial perfusion reserve but preserved peripheral endothelial function in patients with Fabry disease. J Inherit Metab Dis 28:563-573. [C]

Kalliokoski, T., Simell, O., Haaparanta, M., Viljanen, T., Solin, O., Knuuti, J., & Nuutila, P. 2005: An autoradiographic study of ((18)FDG uptake to islets of Langerhans in NOD mouse. Diabetes Res Clin Pract 70: 217-224. [C]

Karlsson, HK., Hällsten, K., *Björnholm, M., *Tsuchida, H., *Chibalin, AV., *Virtanen, KA., Heinonen, OJ., *Lönnqvist, F., Nuutila, P., & *Zierath, JR. 2005: Effects of metformin and rosiglitazone treatment on insulin signaling and glucose uptake in patients with newly diagnosed type 2 diabetes: a randomized controlled study. Diabetes (NY) 54(5): 1459-1467. [C]

*Karrasch, M., *Sinervä, E., *Grönholm, P., Rinne, J., Laine, M. 2005: CERAD test performance in amnestic mild cognitive impairment and Alzheimer's disease. Acta Neurol Scand 111: 172-179.

*Kauppinen-Mäkelin, R., *Sane, T., *Reunanen, A., *Välimäki, MJ., *Niskanen, L., *Markkanen, H., *Löyttyniemi, E., *Ebeling, T., *Jaatinen, P., Laine, H., *Salmela P, *Salmi, J., *Stenman, UH., Viikari, J., & Voutilainen, EA. 2005: Nation-wide survey of mortality in agromegaly. J Clin Endocrinol Metab 90: 4081-4086. [C]

*Kemppainen, J., Aalto, S., *Fujimoto, T., Kalliokoski, KK., *Langsjo, J., Oikonen, V., Rinne, J., Nuutila, P., & Knuuti J. 2005: High-intensity exercise decreases global brain glucose uptake in humans. J Physiol (Lond) 568: 323-332. [C]

Knuuti, J., & *Sipola, P. 2005: Is it time for cardiac innervation imaging? QUARTERLY JOURNAL OF NUCLEAR MEDICINE 49(1): 97-105. [C]

Knuuti, J., *Vanninen, E., *Turjanmaa, V., *Hartiala, H., *Kettunen, R., *Kupari, M., *Loimaala, A., *Rautio, P., *Sipola, P., *Virtanen, KS., & *Syvänne, M. 2005: Sydämen non-invasiivinen kuvantaminen sepelvaltimotaudin diagnostiikassa Suomessa. Suomen Lääkärilehti 20: 2225-2230 [c]

*Koivula, T., *Perhola, O., *Kamarainen, EL., *Lipponen, T., *Vepsäläinen, J., & Solin O. 2005: Simplified synthesis of N-(3-(F-18)fluoropropyl)-2 beta-carbomethoxy-3 beta-(4-fluorophenyl)nortropane (F-18)beta-CFT-FP) using (F18)fluoropropyl tosylate as the labelling reagent. J Labelled Compd & Radiopharm 48 :463-471. [C]

Koort, J., Mäkinen, T., *Suokas, E., *Veiranto, M., *Jalava, J., Knuuti, J., *Törmälä, P., & Aro, H. 2005: Efficacy of ciprofloxacin-releasing bioabsorbable osteoconductive bone defect filler for treatment of experimental osteomyelitis due to staphylococcus aureus. Antimicrob Agents Chemother 49(4): 1502-1508. [C]

*Koponen, H., *Saari, K., *Lindeman, S., *Savolainen, M., Hietala, J, & *Isohanni, M. 2005: Psykoosilääkehoitoon liittyvien metabolisten muutosten seuranta (Follow-up of metabolic parameters in patients with antipsychotic medication. Suomen Lääkäril 60: 1795-1799. [C]

Kotilainen, P., Airas, L., Kojo, T., Kurki, T., Kataja, K., Minn, H.,& Nuutila, P. 2005: Riedel's thyroiditis in a patient with multiple sclerosis. NEUROENDOCRINOLOGY LETTERS 26:68. [C]

Laakso, A., Pohjalainen, T., Bergman, J., Kajander, J., Haaparanta, M., Solin, O., Syvälahti, E., & Hietala, J. 2005: The A1 allele of the human D2 dopamine receptor gene is associated with increased activity of striatal L-amino acid decarboxylase in healthy subjects. PHARMACOGENETICS AND GENOMICS 15: 387-391. [C]

*Lahti, J., *Räikkönen, K., *Ekelund, J., *Peltonen, L., Raitakari, OT., & *Keltinkangas-Järvinen, L. 2005: Novelty seeking: ineraction between parential alcohol use and dopaminen D4 reseptor gene exon III polymorphism over 17 years. PSYCHIATRIC GENETICS 15: 133-139. [C]

*Laitio, T., *Kuusela, T., *Huikuri, H., Jalonen, J., Kentala, E., *Mäkikallio, T., Helenius, H., *Pullisaar O, Hartiala J, & Scheinin H. 2005: Prediction of postoperative myocardial ischemia by fractal heart rate dynamics (in response). Anesth Analg 100:289-290. [C]

Lautamäki, R., Airaksinen, KEJ., *Seppänen, M., *Toikka, J., Luotolahti, M., *Ball, E., *Borra, R., Härkönen, R., Iozzo, P., *Stewart, M., Knuuti, J., & Nuutila, P. 2005: Rosiglitazone improves myocardial glucose uptake in patients with type 2 diabetes and coronary artery disease: a 16-week randomized, double-blind, placebo-controlled study. Diabetes (NY) 54: 2787-2794. [C]

*Lendvai, G., *Velikyan, I., *Bergström, M., *Estrada, S., *Laryea, D., Välilä, M., *Salomäki, S., *Långström, B., & Roivainen, A. 2005: Biodistribution of 68Ga-labelled phosphodiester, phosphorothioate, and 2'-O-methyl phosphodiester oligonucleotides in normal rats. Eur J Pharm Sci 26: 26-38. [C]

*Lund, VE., Kentala, E., Scheinin, H., *Lertola, K., Klossner, J., Aitasalo, K., Sariola-Heinonen, K., & Jalonen, J. 2005: Effect of age and repeated hyberbaric oxygen treatments on vagal tone. Undersea Hyperb Med 32(2): 111-119. [C]

Långsjö, JW., Maksimow, A., Salmi, E., Kaisti, K., Aalto, S., Oikonen, V., Hinkka, S., Aantaa, R, Sipilä, H., Viljanen, T., Parkkola, R., & Scheinin, H. 2005: S-ketamine anes.thesia increases cerebral blood flow in excess of the metabolic needs in humans. Anesthesiology 103(2): 258-268. [C]

Maksimow, A., Kaisti, K., Aalto, S., *Mäenpää, M., Jääskeläinen, S., Hinkka, S., *Martens, S., *Särkelä, M., Viertiö-Oja, H., Kaisti, K., & Scheinin, H. 2005: Correlation of EEG spectral entropy with regional cerebral blood flow during sevoflurane and propofol anaesthesia. Anaesthesia 60: 862-869. [C]

Martikainen, IK., Hagelberg, N., *Mansikka, H., Hietala, J., Någren, K., Scheinin, H, & *Pertovaara, A. 2005: Association of striatal dopamine D2/D3 receptor binding potential with pain but not tactile sensitivity or placebo analgesia. Neurosci Lett 376: 149-153. [C]

Minn, H., & Knuuti, J. 2005: Kliininen PET-kuvantaminen tänään. Pääkirjoitus. Suomen Lääkäril 20: 2187-2188. [c]

Minn, H., Lehtiö, K., & Grenman, R. 2005: In response to Wang et al. Int J Radiat Oncol Biol Phys 61(5): 1608. [C]

Minn H. 2005: PET and SPECT in low-grade glioma. Eur J Radiol 56: 171-178. [C]

Mäkinen, J., Järvisalo, MJ., Pöllanen, P., Perheentupa, A., Irjala, K., Koskenvuo, M., Huhtaniemi, I., & Raitakari, OT. 2005: Increased carotid atherosclerosis in andropausal middle-aged men. Am J Cardiol 45(10): 1603-1608. [C]

Mäkinen, T., Lankinen, P., Pöyhönen, T., Jalava, J., Aro, H., & Roivainen, A. 2005: Comparison of 18F-FDG and 68Ga as tracers in PET imaging of experimental osteomyelitis due to Staphylococcus aureus. Eur J Nucl Med Mol Imaging 32: 1259-1268. [C]

Mäkinen, T., *Veiranto, M., Knuuti, J., *Jalava, J., *Törmälä, P., & Aro, H. 2005: Efficacy of bioabsorbable antibiotic containing bone screw in the prevention of biomaterial-related infection due to staphylococcus aureus. Bone 36: 292-299. [C]

Naum A, Laaksonen M, Tuunanen H, Oikonen V, Teräs M, Kemppainen J, Järvisalo MJ, Nuutila P, Knuuti J. 2005: Motion detection and correction for dynamic 15O-water myocardial perfusion PET studies. Eur J Nucl Med Mol Imaging 32:1378-1383 [C]

Nyman, M., Oikonen, V., *Turiceanu, M., & Scheinin, H., eds. 2005: Abstracts of the X Turku PET Symposium, May 28-31, 2005. Turku, Finland. Turku: Turun yliopisto. Annales Universitatis Turkuensis D. Vol. 660. 122 p. [G]

Pawitan Y., Bettinardi V., & Teräs, M. 2005: NonGaussian smoothing of Low-Count transmission scans for PET in Whole-Body studies. IEEE Trans Med Im 24: 122-129 [C]

Penttilä, J., & Hietala, J. 2005: Mechanisms of action of SSRIs in adolescent depression. J Am Acad Child Adolesc Psychiatry 44(10): 968. [F]

Penttilä, J., Kuusela, T., & Scheinin, H. 2005: Analysis of rapid heart rate variability in the assessment of anticholinergic drug effects in humans. Eur J Clin Pharmacol 61: 559-565. [C]

Penttilä, J., *Laitio, MM., Långsjö, J., Hinkka, S., & Scheinin, H. 2005: Sub-anaesthestic doses of ketamine impair cardiac parasympathetic regulation. Eur J Anaesthesiol 22(10): 808-810. [C]

Penttilä, J., *Mäenpää, M., *Laitio, T., Långsjö, J., Hinkka, S., & Scheinin, H. 2005: Subanaesthetic doses of ketamine impair cardiac parasympathetic regulation. Eur J Anaesthesiol 22: 808-810. [C]

Penttilä, J., Scheinin, H., & Syvälahti, E. 2005: Measurement of anticholinergic effects of psychotic drugs in humans. Pharmacopsychiatry 38: 187-193. [F]

Penttilä, J., Scheinin, H., & Syvälahti, E. 2005: Antikolinergisen lääkevaikutuksen merkitys ja mittaaminen. Suomen Lääkäril 60: 2325-2328. [f]

*Pälvimäki, EP., *Majasuo, H., Syvälahti, E., & Hietala, J. 2005: Serotonin 5-HT2c receptor-mediated phosphoinositide hydrolysis in rat choroid plexus after fluoxetine and citalopram treatments. Pharmacol Res 51(5): 419-425. [C]

Raitakari, OT., Rönnemaa, T., Järvisalo, MJ., *Kaitosaari, T., *Volanen, I., *Kallio, K., *Lagström, H., *Jokinen, E., *Niinikoski, H., Viikari, JSA., & Simell, O. 2005: Endothelial function in healthy 11-year-old children after dietary intervention with onset in infancy. The special Turku coronary risk factor intervention project for children (STRIP). Circulation 112: 3786-3794. [C]

Saarela, K-E., Harju, L., Rajander, J., Lill, J-O., Heselius, S-J.,A. Lindroos, A. & Mattsson, K. 2005: Elemental analyses of pine bark and wood in an environmental study, Science of The Total Environment 343: 231-241. [C]

Saarela, K-E., Harju, L., Lill, J-O., Heselius, S-J., Rajander, J., & Lindroos, A. Quantitative elemental analysis of dry-ashed bark and wood samples of birch, spruce and pine from South-Western Finland using PIXE. 2005: Acta Academiae Aboensis, Ser. B, Math. Phys. 65, No. 4, Åbo, 27 pp. [d]

Salmi, E., Långsjö, J., Aalto, S., Någren, K., Metsähonkala, L., Kaisti, K., Korpi, E., Hietala, J., & Scheinin, H. 2005: Subanesthetic ketamine does not affect 11C-flumazenil binding in humans. Anesth Analg 101: 722-725. [C]

Soilu-Hänninen, M., Airas L, Mononen, I., Heikkilä, A., Viljanen, M., & Hänninen, A. 2005: Vitamin D levels at the onset of multiple sclerosis. MULTIPLE SCLEROSIS 11: 266-271. [C]

Sundell, J., Janatuinen, T., Rönnemaa, T., *Naum, A., Laine, H., Luotolahti, M., Nuutila, P., Raitakari, OT., & Knuuti, J. 2005: Lifetime glycaemic exposure predicts reduced coronary vasoreactivity in type 1 diabetic subjects. Diabetic Med 22: 45-51. [C]

Sundell J. 2005: Obesity and diabetes as risk factors for coronary artery disease: from the epidemiological aspects to the initial vascular mechanisms. Diabetes Obes Metab 7:9-20. [C]

Sundell, J., Laine, H., Raitakari, OT., Luotolahti, M., Nuutila, P., Viikari, J., & Knuuti, J. 2005: Increased lipoprotein(a) is associated with reduced myocardial vasoreactivity in young healthy men. Atherosclerosis 179: 185-191. [C]

Sundell, J., *Vierre, S., & Koistinen, Juhani. 2005: Hyperkalemian aiheuttama bradykardia. Duodecim 121: 1838-1841. [C]

Venojärvi, M., *Puhke, R., Hämäläinen, H., *Marniemi, J., *Rastas, M., *Rusko, H., Nuutila, P., *Hänninen, O., & *Aunola, S. 2005: Role of skeletal muscle-fibre type in regulation of glucose metabolism in middle-aged subjects with impaired glucose tolerance during a long-term exercise and dietary intervention. Diabetes Obes Metab 7(6): 745-754. [C]

*Vikman, S., Airaksinen, J., *Tierala, I., *Peuhkurinen, K., *Majamaa-Voltti, K., *Niemelä, M., Tuunanen, H., *Niemelä, K., & *Nieminen, MS. 2005: Sepelvaltimotautikohtauksen hoito Suomessa. Duodecim 121: 753-759. [c]

Viljanen, APM., Virtanen, KA., Järvisalo, MJ., Hällsten, K., Parkkola, R., Rönnemaa, T., *Lönnqvist, F., Iozzo, P., *Ferrannini, E., & Nuutila, P. 2005: Rosiglitazone treatment increases subcutaneous adipose tissue glucose uptake in parallel with perfusion in patients with type 2 diabetes: A double-blind, randomized study with metformin. J Clin Endocrinol Metab 90(12): 6523-6528. [C]

*Virtanen, KA., Iozzo, P., Hällsten, K., Huupponen, R., Parkkola, R., *Janatuinen, T., *Lönnqvist, F., Viljanen, T., Rönnemaa, T., *Lönnroth, P., Knuuti, J., *Ferrannini, E., & Nuutila, P. 2005: Increased fat mass compensates for insulin resistance in abdominal obesity and type 2 diabetes. A positron-emitting tomography study. Diabetes (NY) 54: 2720-2726. [C]

*Volanen, I., Raitakari, OT., *Vainionpää, R., *Arffman, M., *Aarnisalo, J., *Anglé, S., *Kallio, K., & Simell, O. 2005: Serum lipid profiles poorly correlate with Chlamydia pneumoniae, helicobacter pylori, and cytomegalovirus seropositivity in prospectively followed-up healthy children. Arterioscler Thromb Vasc Biol 25: 827-832. [C]

*Vänttinen, M., Nuutila, P., *Kuulasmaa, T., *Pihlajamäki, J., Hällsten, K., Virtanen, KA., Lautamäki, R., Peltoniemi, P., Takala, T., Viljanen, APM., Knuuti, J., & *Laakso M. 2005: Single nucleotide polymorphisms in the peroxisome proliferator-activated receptor delta gene are associated with skeletal muscle glucose uptake. Diabetes (NY) 54: 3587-3591. [C]

Vänttinen, M., Nuutila, P., *Pihlajamäki, J., Hällsten, K., *Virtanen, KA., Lautamäki, R., Peltoniemi, P., Kemppainen, J., Takala, T., Viljanen, APM., Knuuti, J., & *Laakso, M. 2005: The effect of the Ala12 allele of the peroxisome proliferator-activated receptor-gamma 2 gene on skeletal muscle glucose uptake depends on obesity - a positron emission tomography study. J Clin Endocrinol Metab 90(7): 4249-4254. [C]